Allen Mary Tedd

Allen Mary Tedd

11 Mar 19

Allen Mary Tedd

06 Feb 19

Allen Mary Tedd

12 Oct 18

Allen Mary Tedd

06 Sep 18

Allen Mary Tedd

01 Jul 13

Bailey K Thomas

Bailey K Thomas

11 Mar 22

Bailey K Thomas

19 Aug 21

Bailey K Thomas

20 Aug 20

Bailey K Thomas

20 May 20

Bailey K Thomas

17 May 11

Beechem Joseph M

Beechem Joseph M

28 Jan 22

Beechem Joseph M

15 Jun 21

Beechem Joseph M

03 Sep 20

Beechem Joseph M

13 Mar 20

Beechem Joseph M

07 Feb 18

Brown J. Chad

Brown J. Chad

31 Jan 22

Brown J. Chad

29 Jan 21

Brown J. Chad

03 Jun 20

Brown J. Chad

05 Sep 19

Brown J. Chad

06 Sep 18

Burns Wayne

Burns Wayne

08 Feb 17

Burns Wayne

14 Aug 15

Burns Wayne

11 Feb 15

Burns Wayne

16 Jun 14

Burns Wayne

25 Jun 13

Cowens J Wayne

Cowens J Wayne

04 Feb 14

Cowens J Wayne

25 Jun 13

Crutchfield Bradford

Crutchfield Bradford

24 Nov 21

Crutchfield Bradford

16 Mar 21

Crutchfield Bradford

09 Mar 20

Crutchfield Bradford

21 Aug 12

Crutchfield Bradford

03 Feb 04

Finney Elisha W

Finney Elisha W

12 May 15

Finney Elisha W

26 Nov 12

Finney Elisha W

08 Nov 11

Finney Elisha W

03 Nov 05

Finney Elisha W

22 Nov 04

Fonstad Jennifer Scott

Fonstad Jennifer Scott

03 Jan 14

Fonstad Jennifer Scott

12 Jul 13

Fonstad Jennifer Scott

01 Jul 13

Fonstad Jennifer Scott

25 Jun 13

Foy Teresa M.

Foy Teresa M.

27 Jun 23

Foy Teresa M.

26 Apr 23

Foy Teresa M.

17 Jun 22

Foy Teresa M.

18 Apr 22

Foy Teresa M.

18 Apr 22

Galakatos Nicholas

Galakatos Nicholas

30 Jun 15

Galakatos Nicholas

05 Jan 15

Evnin Luke

04 Oct 10

Galakatos Nicholas

28 Apr 05

Mpm Bioventures Iii Qp Lp

02 Sep 04

Garland Jonathan Todd

Garland Jonathan Todd

28 Aug 23

Garland Jonathan Todd

28 Aug 23

Garland Jonathan Todd

21 Aug 23

Garland Jonathan Todd

19 May 23

Garland Jonathan Todd

27 Apr 22

George Janet

George Janet

06 Sep 24

George Janet

08 May 24

George Janet

11 Mar 24

George Janet

09 Mar 23

George Janet

17 Jun 22

Gerace John D.

Gerace John D.

07 Mar 23

Gerace John D.

11 Jan 23

Gerace John D.

10 Jan 22

Gerace John D.

10 Jan 22

Ghesquiere David W.

Ghesquiere David W.

16 Mar 20

Ghesquiere David W.

08 Mar 18

Ghesquiere David W.

07 Feb 18

Ghesquiere David W.

03 Mar 16

Ghesquiere David W.

25 Nov 13

Gray R Bradley

Gray R Bradley

05 Sep 23

Gray R Bradley

03 Sep 21

Gray R Bradley

18 Feb 20

Gray R Bradley

15 May 19

Gray R Bradley

08 Mar 18

Hershberg Robert

Hershberg Robert

08 Mar 23

Hershberg Robert

06 Jun 22

Hershberg Robert

17 Mar 21

Hershberg Robert

18 Nov 20

Hershberg Robert

27 Apr 20

Johnson James A

Johnson James A

05 Sep 17

Johnson James A

06 Sep 16

Johnson James A

08 Dec 09

Johnson James A

03 Feb 09

Johnson James A

13 Jan 06

Kania Don R

Kania Don R

31 Oct 19

Kania Don R

03 Nov 15

Kania Don R

27 May 15

Kania Don R

11 Feb 14

Kania Don R

14 Feb 11

Kuruvilla Finny

Kuruvilla Finny

03 Jan 14

Kuruvilla Finny

12 Jul 13

Kuruvilla Finny

01 Jul 13

Kuruvilla Finny

25 Jun 13

Malloy Kirk

Malloy Kirk

09 Aug 24

Malloy Kirk

18 Jul 23

Malloy Kirk

15 Sep 21

Malloy Kirk

13 Jan 21

Malloy Kirk

13 Sep 16

Norden Gregory

Norden Gregory

08 May 24

Norden Gregory

27 Jun 23

Norden Gregory

08 Mar 23

Norden Gregory

05 Mar 14

Norden Gregory

03 Mar 09

Nova Tina Susan

Nova Tina Susan

16 Jun 20

Nova Tina Susan

03 Sep 19

Nova Tina Susan

15 Jun 18

Nova Tina Susan

11 Jun 13

Nova Tina Susan

01 Aug 06

Riordan Gary S

Riordan Gary S

25 Jun 13

Rollison Dana E.

Rollison Dana E.

09 Mar 23

Rollison Dana E.

09 Mar 22

Rollison Dana E.

17 Jun 21

Rollison Dana E.

09 Mar 21

Rollison Dana E.

09 Mar 21

Saunders Barney

Saunders Barney

03 Mar 17

Saunders Barney

03 Mar 16

Saunders Barney

11 Aug 15

Saunders Barney

11 Feb 15

Saunders Barney

04 Sep 14

Seeley Bruce J.

Seeley Bruce J.

11 Mar 22

Seeley Bruce J.

17 May 18

Seeley Bruce J.

03 Oct 17

Seeley Bruce J.

01 Jul 16

Seeley Bruce J.

04 Feb 14

Surace-smith Kathryn

Surace-smith Kathryn

07 Nov 07

Surace-smith Kathryn

02 Nov 06

Surace-smith Kathryn

03 May 06

Surace-smith Kathryn

23 Feb 06

Annual Statement Of Changes In Beneficial Ownership Of Securities.

20 Jan 06

Waite Charles P Jr

Waite Charles P Jr

17 Jun 22

Waite Charles P Jr

26 Jun 12

Waite Charles P Jr

15 Mar 12

Ovp Venture Partners Vi Lp

13 Dec 11

Ovp Venture Partners Vi Lp

09 Dec 11

Young William

Young William

30 Jun 21

Young William

23 Jul 20

Young William

26 Aug 19

Young William

04 Jan 17

Young William

10 Jun 10

Alger Associates Inc

Amended Statement Of Beneficial Ownership Of More Than 5%.

10 Nov 22

08 Oct 21

Amended Statement Of Beneficial Ownership Of More Than 5%.

10 Jun 21

16 Feb 21

Alger Associates Inc

18 Jan 18

Prosight Management, Lp

Quarterly Holdings Report

15 May 24

13 Feb 24

Quarterly Holdings Report

13 Nov 20

Amended Statement Of Beneficial Ownership Of More Than 5%.

14 Feb 19

30 Jan 17

Wygod Martin J

Amended Statement Of Beneficial Ownership Of More Than 5%.

22 Nov 23

Wygod Martin J

12 Jan 22

Wygod Martin J

23 Mar 10

Wygod Martin J

05 Dec 08

14 Feb 07

Nikko Asset Management Americas, Inc.

Amended Statement Of Beneficial Ownership Of More Than 5%.

10 Feb 23

Amended Statement Of Beneficial Ownership Of More Than 5%.

11 Feb 21

Amended Statement Of Beneficial Ownership Of More Than 5%.

12 Feb 20

Quarterly Holdings Report

28 Oct 16

Quarterly Holdings Report

08 Feb 10

Platinum Investment Management Ltd

06 Nov 24

Quarterly Holdings Report

14 Nov 17

13 Feb 14

15 Feb 13

13 Feb 07

Draper Fisher Jurvetson Fund Vii, L.p.

Amended Statement Of Beneficial Ownership Of More Than 5%.

28 Jan 16

Draper Fisher Jurvetson Fund Vii, L.p.

03 Jan 14

Draper Fisher Jurvetson Fund Vii, L.p.

01 Jul 13

01 Feb 12

Draper Fisher Jurvetson Fund Vii, L.p.

01 Feb 11

Ark Investment Management Llc

29 Jan 24

10 Sep 21

Amended Statement Of Beneficial Ownership Of More Than 5%.

16 Feb 21

Quarterly Holdings Report

13 May 19

14 Feb 19

Wellington Management Group Llp

12 Feb 19

12 Mar 12

14 Feb 08

12 Feb 02

13 Feb 01

Integrated Core Strategies (us) Llc

14 Feb 22

04 Feb 22

07 Dec 21

16 Apr 12

10 Jun 09

Ra Capital Management, L.p.

Amended Statement Of Beneficial Ownership Of More Than 5%.

13 Nov 24

Ra Capital Management, L.p.

25 Jul 23

Amended Statement Of Beneficial Ownership Of More Than 5%.

14 Nov 22

16 Feb 21

Amended Statement Of Beneficial Ownership Of More Than 5%.

14 Feb 14

Foresite Capital Fund Ii, L.p.

Foresite Capital Management I, Llc

19 Mar 20

Foresite Capital Management I, Llc

16 Sep 19

Foresite Capital Management Ii, Llc

19 Aug 16

Amended Statement Of Beneficial Ownership Of More Than 5%.

12 Feb 16

09 Sep 15

Avidity Partners Management Lp

30 Aug 24

13 Feb 24

13 Feb 24

Amended Statement Of Beneficial Ownership Of More Than 5%.

14 Feb 22

30 Dec 20

Flynn James E

14 Nov 24

10 Feb 20

16 Apr 15

Flynn James E

31 Dec 08

Flynn James E

24 May 06

Morgan Stanley

Prospectus Filed Pursuant To Rule 424(b)(2).

29 Oct 24

Prospectus Filed Pursuant To Rule 424(b)(2).

07 May 24

Prospectus Filed Pursuant To Rule 424(b)(2).

26 Dec 23

Prospectus Filed Pursuant To Rule 424(b)(2).

30 Aug 22

Free Writing Prospectuses - Filing Under Securities Act Rules 163/433.

30 Aug 21

Levin Capital Strategies, L.p.

Levin Capital Strategies, L.p.

02 Aug 18

Levin Capital Strategies, L.p.

12 Feb 18

05 Feb 16

Quarterly Holdings Report

12 Feb 13

Quarterly Holdings Report

12 Nov 10

Sumitomo Mitsui Trust Holdings, Inc.

05 Feb 21

05 Feb 21

12 Feb 20

Report Of Foreign Private Issuer Pursuant To Rules 13a-16 And 15d-16.

13 May 11

Report Of Foreign Private Issuer Pursuant To Rules 13a-16 And 15d-16.

26 Nov 10

Blackrock Inc.

31 Jan 19

30 Jan 19

08 Jul 16

04 Feb 11

09 Feb 07

Titanite Investment Management Lp

25 Jan 24

21 Aug 23

Fmr Llc

09 Feb 22

14 Feb 14

16 Feb 10

10 Nov 03

11 Feb 97

Redmile Group, Llc

Quarterly Holdings Report

14 Nov 22

Amended Statement Of Beneficial Ownership Of More Than 5%.

14 Feb 22

16 Feb 21

Redmile Group, Llc

16 Sep 16

Quarterly Holdings Report

14 Aug 12

Cadian Capital Management, Lp

13 Feb 20

Preliminary Merger Proxies.

11 May 12

Amended Statement Of Beneficial Ownership Of More Than 5%.

14 Feb 12

Quarterly Holdings Report

15 Aug 11

Amended Statement Of Beneficial Ownership Of More Than 5%.

14 Feb 11

Vanguard Group Inc

11 Feb 19

11 Feb 16

10 Feb 16

12 Feb 14

12 Feb 14

Clarus Lifesciences Ii, L.p.

Amended Statement Of Beneficial Ownership Of More Than 5%.

09 Feb 18

Clarus Lifesciences Ii, L.p.

05 Feb 16

Amended Statement Of Beneficial Ownership Of More Than 5%.

05 Feb 16

Clarus Lifesciences Ii, L.p.

11 Jun 14

Acquired More Than 5% Ownership Of Any Class Of A Company's Securities.

20 Nov 13

Farallon Capital Partners, L.p.

10 May 21

Farallon Capital Partners, L.p.

01 Jul 10

Farallon Capital Partners Lp

01 Jul 05

Farallon Partners L L C/ca

18 Nov 03

Farallon Partners L L C/ca

16 Oct 03

Polar Capital Holdings Plc

13 Nov 24

Quarterly Holdings Report

14 Feb 24

Quarterly Holdings Report

15 May 23

14 Feb 22

Quarterly Holdings Report

15 Nov 21

Pura Vida Investments, Llc

Amended Statement Of Beneficial Ownership Of More Than 5%.

25 Jul 23

14 Feb 23

11 Aug 21

12 Feb 21

17 Jan 20

Ovp Venture Partners Vi Lp

Ovp Venture Partners Vi Lp

03 Jan 14

Ovp Venture Partners Vi Lp

15 Mar 12

Ovp Venture Partners Vi Lp

16 Nov 10

Ovp Venture Partners Vi Lp

10 Nov 10

Amendment To The Form D Notice Of An Exempt Offering Of Securities Under Regulation D.

12 Jul 02