Opko Health, Inc.

Pharmaceutical Preparations

NASDAQ.OPK

4400 Biscayne Blvd., Miami, FL, 33137

Amount	Security	Market Value
240	COM	$358
30,000	COM	$44,700
41,309	COM	$61,757
49,205	COM	$73,315
28,619,929	COM	$42,643,694
4,230,700	COM	$6,303,743
134,700	COM	$200,703
50,307	COM	$74,957
80,330	COMMON STOCK	$119,692
174,157	COM	$259,494
208,999	COM	$311,409
41,289	COM	$61,521
11,185	COM	$16,666
206,314	COM	$308,439
11,380	COM	$16,957
278,900	COM	$415,561
633,500	CALL	$943
61,176	COM	$91,152
1,796	COM	$2,676
40,650	COM	$60,569
104,191	COM	$155,245
384	Common Stock	$572
17,000	COM	$21,250
3,000	COM	$3,750
45,062	COM	$67,142
24,945	COM	$37,168
14,960	COM	$22,290
505,007	COMMON	$752,460
2,688	COM	$4,000
27,689	COM	$41,257
32,000	COMMON	$47,680
697,896	COM	$1,039,865
1,096,600	PUT	$1,633
30,000	COM	$44,700
28,936	COM	$43,115
40,717	COM	$60,668
121,523	COM	$181,069
12,383	Stock	$18,451
89,728	COM	$133,695
6,000	Stock	$8,940
286	Stock	$426
616	COM	$918
2,330	COM	$3,472
726,582	COM	$1,082,607
1,713,845	COM	$2,566,610
25,843	COM	$38,506
2,742,874	COM	$4,086,882
103,561	HEALTH INC COM	$154
10,163	COM	$15,143
107,381	COM	$157

Amount	Security	Market Value
240	COM	$358
30,000	COM	$44,700
41,309	COM	$61,757
49,205	COM	$73,315
28,619,929	COM	$42,643,694
4,230,700	COM	$6,303,743
134,700	COM	$200,703
50,307	COM	$74,957
80,330	COMMON STOCK	$119,692
174,157	COM	$259,494
208,999	COM	$311,409
41,289	COM	$61,521
11,185	COM	$16,666
206,314	COM	$308,439
11,380	COM	$16,957
278,900	COM	$415,561
633,500	CALL	$943
61,176	COM	$91,152
1,796	COM	$2,676
40,650	COM	$60,569
104,191	COM	$155,245
384	Common Stock	$572
17,000	COM	$21,250
3,000	COM	$3,750
45,062	COM	$67,142
24,945	COM	$37,168
14,960	COM	$22,290
505,007	COMMON	$752,460
2,688	COM	$4,000
27,689	COM	$41,257
32,000	COMMON	$47,680
697,896	COM	$1,039,865
1,096,600	PUT	$1,633
30,000	COM	$44,700
28,936	COM	$43,115
40,717	COM	$60,668
121,523	COM	$181,069
12,383	Stock	$18,451
89,728	COM	$133,695
6,000	Stock	$8,940
286	Stock	$426
616	COM	$918
2,330	COM	$3,472
726,582	COM	$1,082,607
1,713,845	COM	$2,566,610
25,843	COM	$38,506
2,742,874	COM	$4,086,882
103,561	HEALTH INC COM	$154
10,163	COM	$15,143
107,381	COM	$157

Institutional Owners