Xenon Pharmaceuticals Inc.

Pharmaceutical Preparations

NASDAQ.XENE

200 - 3650 Gilmore Way, Burnaby, A1, V5g 48w

Amount	Security	Market Value
993,679	COM	$39,121,142
20,430	COM	$789,620
24,778	COM	$975,510
25,200	COM	$992,124
48,668	COM	$1,916,059
6,884	COM	$271,023
2,425	COM	$95,472
13,009	COM	$512,164
148,736	COM	$5,855,736
24,327	COM	$957,754
30,145	COM	$1,186,809
10,629	COM	$418,464
259,025	COM	$10,816,884
24,557	COM	$966,809
2,681,537	COM	$105,572,112
5,581	COM	$219,724
55,120	COM	$2,170,076
3,648	COM	$143,622
27,270	COM	$1,074
100,982	COM	$3,975,661
3,120	COM	$122,834
16,089	COM	$633
19,051	COM	$750,038
20,231	COM	$796,494
9,554	COM	$373,189
179,878	COM	$7,081,797
15,911	COM	$628
40,376	COM	$1,589,603
3,711	COM	$146,102
576,661	COM	$22,703,142
5,254	COM	$206,850
527,700	COM	$20,775,549
20,866	Common	$821
984,019	COM	$38,740,828
12,388	COM	$487,716
113,797	COMMON	$4,480
19,744	COM	$777,321
279,513	COM	$11,004,427
37,458	COM	$1,475
35,000	COM	$1,377,950
20,298	COM	$799,132
3,472	Equity	$136,693
27,158	COM	$1,069
14,503	COM	$570,983
463,861	COM	$18,261,389
736,200	COM	$28,984,194
64,373	COM	$2,534,365
262,631	COM	$10,340
243,141	COM	$9,572,461
66,378	COM	$2,613,302

Amount	Security	Market Value
993,679	COM	$39,121,142
20,430	COM	$789,620
24,778	COM	$975,510
25,200	COM	$992,124
48,668	COM	$1,916,059
6,884	COM	$271,023
2,425	COM	$95,472
13,009	COM	$512,164
148,736	COM	$5,855,736
24,327	COM	$957,754
30,145	COM	$1,186,809
10,629	COM	$418,464
259,025	COM	$10,816,884
24,557	COM	$966,809
2,681,537	COM	$105,572,112
5,581	COM	$219,724
55,120	COM	$2,170,076
3,648	COM	$143,622
27,270	COM	$1,074
100,982	COM	$3,975,661
3,120	COM	$122,834
16,089	COM	$633
19,051	COM	$750,038
20,231	COM	$796,494
9,554	COM	$373,189
179,878	COM	$7,081,797
15,911	COM	$628
40,376	COM	$1,589,603
3,711	COM	$146,102
576,661	COM	$22,703,142
5,254	COM	$206,850
527,700	COM	$20,775,549
20,866	Common	$821
984,019	COM	$38,740,828
12,388	COM	$487,716
113,797	COMMON	$4,480
19,744	COM	$777,321
279,513	COM	$11,004,427
37,458	COM	$1,475
35,000	COM	$1,377,950
20,298	COM	$799,132
3,472	Equity	$136,693
27,158	COM	$1,069
14,503	COM	$570,983
463,861	COM	$18,261,389
736,200	COM	$28,984,194
64,373	COM	$2,534,365
262,631	COM	$10,340
243,141	COM	$9,572,461
66,378	COM	$2,613,302

Institutional Owners